Lead investigator Rowan T. Chlebowski, MD, PhD, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center in Torrance, California , and his team mates applied the data from the Women”s Health Initiative (WHI) calcium plus vitamin D supplementation trial.
The researchers studied a subgroup of 1,911 postmenopausal women for this recent study. These women had been believed to receive calcium carbonate with vitamin D3 daily or placebo and underwent serial joint symptom assessment.
Among the daily supplement use and placebo groups, pain at joints and swelled up baseline entry was comparable, at a figure of 70 percent or more. Post two years, analysis did not reveal any statistically significant difference regarding the frequency or severity of joint pain or swelling at baseline.
The researchers or the investigators did not find any interaction with age, BMI, race/ethnicity, or physical activity. No particular interaction was seen with non-protocol vitamin D supplement use at entry.
Anyhow, the participants using non-protocol calcium supplements during entry showed less joint pain in comparison with those in the placebo group. The effect of calcium and vitamin D supplementation individually on joint pains was not evident as both were given combined in a single pill in this trial.
The study is published in the Journal of the Academy of Nutrition and Dietetics.